課程名稱 |
微生物學及免疫學甲 MICROBIOLOGY ,IMMUNOLOGY (A) & LAB. |
開課學期 |
94-2 |
授課對象 |
醫學院 法醫學研究所 |
授課教師 |
陳小梨 |
課號 |
Med3015 |
課程識別碼 |
401 353A0 |
班次 |
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學分 |
6 |
全/半年 |
半年 |
必/選修 |
必修 |
上課時間 |
星期一1,2(8:10~10:00)星期三1,2,3,4(8:10~12:10)星期四1,2,3,4(8:10~12:10) |
上課地點 |
基501四東 |
備註 |
與醫學系合班上課與薛博仁、葉秀慧、陳培哲、王維恭、王錦堂、許翠瑛、張 鑫、董馨蓮、李財坤、繆希椿、潘子明、王萬波、伍安怡、蔡錦華、陳美如、賈景山、許秉寧、鄧述諄、李建國合開先修科目:普通化學丙與有機化學與生物化學(適用本系)。 |
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課程簡介影片 |
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核心能力關聯 |
本課程尚未建立核心能力關連 |
課程大綱
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課程概述 |
課程內容主要詳細探討各種細菌、黴菌及病毒等之Structure, viral factors, growth, genomic organization, toxin, replication, cell cycle, pathogenesis immunity等,與臨床上細菌偵測方法、臨床症狀與目前治療方向方法等。 |
課程目標 |
對於微生物及免疫的多樣性給予一系統性的介紹,透過深入淺出的課程內容,使學生對微生物與免疫對其與宿主間交互作用等問題有一概括性的整體認識。 |
課程要求 |
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預期每週課後學習時數 |
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Office Hours |
另約時間 |
指定閱讀 |
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參考書目 |
Medical Microbiology (5th) Patrick R. Murray et al., 2005 ;
Immunobiology (6th) Charles A. Janeway et al., 2005 |
評量方式 (僅供參考) |
No. |
項目 |
百分比 |
說明 |
1. |
第一次月考 |
17% |
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2. |
第二次月考 |
17% |
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3. |
第三次月考 |
17% |
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4. |
第四次月考 |
17% |
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5. |
實驗跑檯 |
8% |
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6. |
實驗筆試 |
16% |
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7. |
小組報告 |
8% |
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週次 |
日期 |
單元主題 |
第1週 |
2/20,2/22,2/23 |
01. Introduction to medical microbiology
02. Mechanisms of bacterial pathogenesis
03. Bacterial morphology and structure
04. Bacterial metabolism and physiology (I)
05. Bacterial metabolism and physiology (II)
小組報告規則說明
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第2週 |
2/27,3/01,3/02 |
a. Introduction to immunology
b. Structure of the antibody molecule and Ig gene
06. Bacterial genetics (I)
07. Bacterial genetics (II) & Bacteriophage
08. Action of physical and chemical agents
09. Antibiotics and chemotherapy
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第3週 |
3/06,3/08,3/09 |
c. Components of immune system
d. Principle of innate and adaptive immune response
10. Staphylococci and related microorganisms
11. Streptococci and other gram-positive cocci.
12. Spore-forming bacilli
13. Corynebacteria, Mycobacteria
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第4週 |
3/13,3/15,3/16 |
e. Antigen recognition by B lymphocytes
f. Antigen recognition by T lymphocytes (I)
14. Neisseriae
15. Oral microbiology
16. Glucose-nonfermenting Gram (-)bacilli
17. Legionella
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第5週 |
3/20,3/22,3/23 |
g. Antigen recognition by T lymphocytes (II)
h. Signaling through the immune system receptor
REVIEW I (microbiology 1-13, immunology a-d)
18. Enterobacteriaceae (I)
19. Enterobacteriaceae (II)
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第6週 |
3/27,3/29,3/30 |
i. The development of B lymphocytes
j. The development of T lymphocytes
20. Vibrio, Campylobacter
21. Helicobacter
22. Small Gram(-) bacilli
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第7週 |
4/03,4/05,4/06 |
23. Spirochetes
24. Mycoplasmas
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第8週 |
4/10,4/12,4/13 |
k. T cell mediated immunity(I)
l. T cell mediated immunity(II)
25. Mycology
26. Systemic mycoses and opportunistic infections
27. Cutaneous mycoses
28. Subcutaneous mycoses
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第9週 |
4/17,4/19,4/20 |
m. The humoral immune response
n. Host defense against infection (I)
29. Rickettsiae
30. Chlamydiae
31. General properties of animal viruses (I)
32. General properties of animal viruses (II)
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第10週 |
4/24,4/26,4/27 |
o. Host defense against infection (II)
p. Failure of host defense mechanisms
REVIEW II (microbiology 14-30)
33. General properties of animal viruses (III)
34. General properties of animal viruses (IV)
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第11週 |
5/01,5/03,5/04 |
q. Clinical immunology (I): Hypersensitivity
r. Clinical immunology (II): Autoimmunity
s. Clinical immunology (III):
Transplantation and tumor
t. Vaccine and Immunotherapy
35. Papovaviruses: Polyomaviruses, Papillomaviruses
36. Adenoviruses
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第12週 |
5/08,5/10,5/11 |
37. Poxviruses, Parvoviruses
38. Herpesviruses (I)
39. Herpesviruses (II)
40. Herpesviruses (III)
41. Reovirus and Rotavirus
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第13週 |
5/15,5/17,5/18 |
42. Picornaviruses
43. Togaviruses and Flaviviruses
REVIEW III (immunology e-t)
44. Emerging infection agents
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第14週 |
5/22,5/24,5/25 |
45. Hepatitis viruses (I)
46. Hepatitis viruses (II)
47. Paramyxoviruses
48. Orthomyxoviruses
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第15週 |
5/29,5/31,6/01 |
49. Coronaviruses and Bunyaviruses
50. Rhabdoviruses and Filoviruses
51. Retroviruses
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第16週 |
6/05,6/07,6/08 |
52. Human immunodeficient virus
53.Unconventional slow viruses: Prions
54. Biological products
小組報告
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第17週 |
6/12,6/14,6/15 |
FINAL LAB EXAMINATION |
第18週 |
6/19,6/21,6/22 |
FINAL EXAMINATION |
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